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PKM2 and HIF-1α regulation in prostate cancer cell lines

Prostate cancer (PCA) is one of the most common cancer types in men, with cancer progression being linked to hypoxia and the induction of hypoxia-inducible factor (HIF).We investigated the expression of pyruvate kinase M2 (PKM2), its regulation by HIF isoforms 1α and 2α, and its role in HIF stabiliz...

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Detalles Bibliográficos
Autores principales:	Hasan, Diya, Gamen, Elisabetta, Abu Tarboush, Nafez, Ismail, Yazan, Pak, Oleg, Azab, Belal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138389/ https://www.ncbi.nlm.nih.gov/pubmed/30216369 http://dx.doi.org/10.1371/journal.pone.0203745

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