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Queuosine‐modified tRNAs confer nutritional control of protein translation

Global protein translation as well as translation at the codon level can be regulated by tRNA modifications. In eukaryotes, levels of tRNA queuosinylation reflect the bioavailability of the precursor queuine, which is salvaged from the diet and gut microbiota. We show here that nutritionally determi...

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Detalles Bibliográficos
Autores principales: Tuorto, Francesca, Legrand, Carine, Cirzi, Cansu, Federico, Giuseppina, Liebers, Reinhard, Müller, Martin, Ehrenhofer‐Murray, Ann E, Dittmar, Gunnar, Gröne, Hermann‐Josef, Lyko, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138434/
https://www.ncbi.nlm.nih.gov/pubmed/30093495
http://dx.doi.org/10.15252/embj.201899777