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Queuosine‐modified tRNAs confer nutritional control of protein translation
Global protein translation as well as translation at the codon level can be regulated by tRNA modifications. In eukaryotes, levels of tRNA queuosinylation reflect the bioavailability of the precursor queuine, which is salvaged from the diet and gut microbiota. We show here that nutritionally determi...
Autores principales: | Tuorto, Francesca, Legrand, Carine, Cirzi, Cansu, Federico, Giuseppina, Liebers, Reinhard, Müller, Martin, Ehrenhofer‐Murray, Ann E, Dittmar, Gunnar, Gröne, Hermann‐Josef, Lyko, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138434/ https://www.ncbi.nlm.nih.gov/pubmed/30093495 http://dx.doi.org/10.15252/embj.201899777 |
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