SHLD2/FAM35A co‐operates with REV7 to coordinate DNA double‐strand break repair pathway choice

DNA double‐strand breaks (DSBs) can be repaired by two major pathways: non‐homologous end‐joining (NHEJ) and homologous recombination (HR). DNA repair pathway choice is governed by the opposing activities of 53BP1, in complex with its effectors RIF1 and REV7, and BRCA1. However, it remains unknown h...

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Detalles Bibliográficos
Autores principales: Findlay, Steven, Heath, John, Luo, Vincent M, Malina, Abba, Morin, Théo, Coulombe, Yan, Djerir, Billel, Li, Zhigang, Samiei, Arash, Simo‐Cheyou, Estelle, Karam, Martin, Bagci, Halil, Rahat, Dolev, Grapton, Damien, Lavoie, Elise G, Dove, Christian, Khaled, Husam, Kuasne, Hellen, Mann, Koren K, Klein, Kathleen Oros, Greenwood, Celia M, Tabach, Yuval, Park, Morag, Côté, Jean‐Francois, Masson, Jean‐Yves, Maréchal, Alexandre, Orthwein, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138439/
https://www.ncbi.nlm.nih.gov/pubmed/30154076
http://dx.doi.org/10.15252/embj.2018100158

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