In-vitro generation of interleukin-10 secreting B-regulatory cells from donor adipose tissue derived mesenchymal stem cells and recipient peripheral blood mononuclear cells for potential cell therapy

BACKGROUND: Interleukin-10 secreting B-cells are a major subset of B-regulatory cells (B-regs), commonly recognized as CD19(+)/38(hi)/24(hi)/IL10(+). They carry out immunomodulation by release of specific cytokines and/or cell-to-cell contact. We have generated B-regs in-vitro from donor adipose tis...

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Detalles Bibliográficos
Autores principales: Gupte, Kunal S., Vanikar, Aruna V., Trivedi, Hargovind L., Patel, Chetan N., Patel, Jignesh V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138595/
https://www.ncbi.nlm.nih.gov/pubmed/28411882
http://dx.doi.org/10.1016/j.bj.2017.01.003

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