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Skeletal Muscle Dystrophy mutant of lamin A alters the structure and dynamics of the Ig fold domain
Mutations in the different domains of A-type lamin proteins cause a diverse plethora of diseases collectively termed as laminopathies which can affect multiple organs. Ig fold is one such domain of lamin A which is implicated in numerous nuclear interactions wherein the mutations lead to different l...
Autores principales: | Dutta, Subarna, Das, Jitendra K., Maganti, Lakshmi, Bhattacharyya, Maitree, Bhattacharyya, Dhananjay, Mukherjee, Sujoy, Sengupta, Kaushik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138676/ https://www.ncbi.nlm.nih.gov/pubmed/30218058 http://dx.doi.org/10.1038/s41598-018-32227-2 |
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