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Proline provides site-specific flexibility for in vivo collagen
Fibrillar collagens have mechanical and biological roles, providing tissues with both tensile strength and cell binding sites which allow molecular interactions with cell-surface receptors such as integrins. A key question is: how do collagens allow tissue flexibility whilst maintaining well-defined...
Autores principales: | Chow, Wing Ying, Forman, Chris J., Bihan, Dominique, Puszkarska, Anna M., Rajan, Rakesh, Reid, David G., Slatter, David A., Colwell, Lucy J., Wales, David J., Farndale, Richard W., Duer, Melinda J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138679/ https://www.ncbi.nlm.nih.gov/pubmed/30218106 http://dx.doi.org/10.1038/s41598-018-31937-x |
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