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Nicotine and sleep deprivation: impact on pain sensitivity and immune modulation in rats
Repeated nicotine administration has been associated with increased paradoxical sleep in rats and antinociceptive properties, whereas paradoxical sleep deprivation (PSD) elicits pronociceptive and inflammatory responses. Thus, we aimed to evaluate the effect of repeated nicotine administration and i...
Autores principales: | Hirotsu, Camila, Pedroni, Matheus Negrao, Berro, Laís Fernanda, Tufik, Sergio, Andersen, Monica Levy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138689/ https://www.ncbi.nlm.nih.gov/pubmed/30218019 http://dx.doi.org/10.1038/s41598-018-32276-7 |
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