Alternative functions for the multifarious inflammasome

The inflammasome has been mainly studied in innate immune cells in which it senses microbes and cellular damage, and induces secretion of pro-inflammatory cytokines. This process induces an inflammatory response that is critical for the resolution of infections and repair of tissue damage following...

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Detalles Bibliográficos
Autores principales: Martel, Jan, Lai, Hsin-Chih, Ko, Yun-Fei, Young, John D., Ojcius, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2016
Materias:
Short Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138791/
https://www.ncbi.nlm.nih.gov/pubmed/27621119
http://dx.doi.org/10.1016/j.bj.2016.06.001
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author Martel, Jan
Lai, Hsin-Chih
Ko, Yun-Fei
Young, John D.
Ojcius, David M.
author_facet Martel, Jan
Lai, Hsin-Chih
Ko, Yun-Fei
Young, John D.
Ojcius, David M.
author_sort Martel, Jan
collection PubMed
description The inflammasome has been mainly studied in innate immune cells in which it senses microbes and cellular damage, and induces secretion of pro-inflammatory cytokines. This process induces an inflammatory response that is critical for the resolution of infections and repair of tissue damage following injury. Recent studies indicate that inflammasome complex formation also participates in many other cellular and physiological processes beyond modulation of inflammation, such as autophagy, metabolism, eicosanoids production, and phagosome maturation.
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spelling pubmed-61387912018-09-27 Alternative functions for the multifarious inflammasome Martel, Jan Lai, Hsin-Chih Ko, Yun-Fei Young, John D. Ojcius, David M. Biomed J Short Review The inflammasome has been mainly studied in innate immune cells in which it senses microbes and cellular damage, and induces secretion of pro-inflammatory cytokines. This process induces an inflammatory response that is critical for the resolution of infections and repair of tissue damage following injury. Recent studies indicate that inflammasome complex formation also participates in many other cellular and physiological processes beyond modulation of inflammation, such as autophagy, metabolism, eicosanoids production, and phagosome maturation. Chang Gung University 2016-06 2016-08-23 /pmc/articles/PMC6138791/ /pubmed/27621119 http://dx.doi.org/10.1016/j.bj.2016.06.001 Text en © 2016 Chang Gung University. Publishing services by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Short Review
Martel, Jan
Lai, Hsin-Chih
Ko, Yun-Fei
Young, John D.
Ojcius, David M.
Alternative functions for the multifarious inflammasome
title Alternative functions for the multifarious inflammasome
title_full Alternative functions for the multifarious inflammasome
title_fullStr Alternative functions for the multifarious inflammasome
title_full_unstemmed Alternative functions for the multifarious inflammasome
title_short Alternative functions for the multifarious inflammasome
title_sort alternative functions for the multifarious inflammasome
topic Short Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138791/
https://www.ncbi.nlm.nih.gov/pubmed/27621119
http://dx.doi.org/10.1016/j.bj.2016.06.001
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