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Mutational Mtc6p attenuates autophagy and improves secretory expression of heterologous proteins in Kluyveromyces marxianus

BACKGROUND: The yeast Kluyveromyces marxianus is an emerging cell factory for heterologous protein biosynthesis and its use holds tremendous advantages for multiple applications. However, which genes influence the productivity of desired proteins in K. marxianus has so far been investigated by very...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Mo, Wen-Juan, Shi, Tian-Fang, Wang, Meng-Zhu, Zhou, Jun-Gang, Yu, Yao, Yew, Wen-Shan, Lu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138896/
https://www.ncbi.nlm.nih.gov/pubmed/30217195
http://dx.doi.org/10.1186/s12934-018-0993-9