Cargando…

MicroRNA let-7b inhibits keratinocyte differentiation by targeting IL-6 mediated ERK signaling in psoriasis

BACKGROUND: The extensive involvement of microRNA (miRNA) in the pathophysiology of psoriasis is well documented. However, in order for this information to be useful in therapeutic manipulation of miRNA levels, it is essential that detailed functional mechanisms are elucidated. This study aimed to e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yan, Liu, Liu, Bian, Chunxiang, Diao, Qingchun, Nisar, Muhammad Farrukh, Jiang, Xuemei, Bartsch, Jörg W., Zhong, Maojiao, Hu, Xiangyu, Zhong, Julia Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138911/ https://www.ncbi.nlm.nih.gov/pubmed/30219085 http://dx.doi.org/10.1186/s12964-018-0271-9

Ejemplares similares

Heme oxygenase 1 facilitates cell proliferation via the B-Raf-ERK signaling pathway in melanoma
por: Liu, Liu, et al.
Publicado: (2019)

The p75(NTR) and its carboxyl‐terminal fragment exert opposing effects on melanoma cell proliferation and apoptosis via modulation of the NF‐κB pathway
por: Zhong, Maojiao, et al.
Publicado: (2020)

UVA Irradiation Enhances Brusatol-Mediated Inhibition of Melanoma Growth by Downregulation of the Nrf2-Mediated Antioxidant Response
por: Wang, Mei, et al.
Publicado: (2018)

Telomerase reverse transcriptase mediates EMT through NF-κB signaling in tongue squamous cell carcinoma
por: Wu, Yan, et al.
Publicado: (2017)

IL-36 signaling in keratinocytes controls early IL-23 production in psoriasis-like dermatitis
por: Goldstein, Jérémie D, et al.
Publicado: (2020)

The EGFR-ERK/JNK-CCL20 Pathway in Scratched Keratinocytes May Underpin Koebnerization in Psoriasis Patients
por: Furue, Kazuhisa, et al.
Publicado: (2020)

Dithranol targets keratinocytes, their crosstalk with neutrophils and inhibits the IL-36 inflammatory loop in psoriasis
por: Benezeder, Theresa, et al.
Publicado: (2020)

The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function
por: Pfaff, Carolina M., et al.
Publicado: (2017)

MicroRNA Let-7 Induces M2 Macrophage Polarization in COPD Emphysema Through the IL-6/STAT3 Pathway
por: Liu, Tingting, et al.
Publicado: (2023)

Interleukin-17A and Keratinocytes in Psoriasis
por: Furue, Masutaka, et al.
Publicado: (2020)

Crosstalk: keratinocytes and immune cells in psoriasis
por: Kamata, Masahiro, et al.
Publicado: (2023)

Updated Perspectives on Keratinocytes and Psoriasis: Keratinocytes are More Than Innocent Bystanders
por: Ortiz-Lopez, Laura I, et al.
Publicado: (2022)

Evidence that a neutrophil–keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis
por: Reich, Kristian, et al.
Publicado: (2015)

Evaluation of the effects of IL-22 on the proliferation and differentiation of keratinocytes in vitro
por: Zhuang, Le, et al.
Publicado: (2020)

IL-36γ inhibits differentiation and induces inflammation of keratinocyte via Wnt signaling pathway in psoriasis
por: Wang, Wenming, et al.
Publicado: (2017)

miR-124-3p Delivered Using Exosomes Attenuates the Keratinocyte Response to IL-17A Stimulation in Psoriasis
por: Liu, Simin, et al.
Publicado: (2022)

Advances in the pathogenesis of psoriasis: from keratinocyte perspective
por: Zhou, Xue, et al.
Publicado: (2022)

MicroRNA‐181b negatively regulates the proliferation of human epidermal keratinocytes in psoriasis through targeting TLR4
por: Feng, Cheng, et al.
Publicado: (2016)

MicroRNA-17-92 cluster promotes the proliferation and the chemokine production of keratinocytes: implication for the pathogenesis of psoriasis
por: Zhang, Weigang, et al.
Publicado: (2018)

Expression of IL-1 family members upon stimulation with IL-17 differs in keratinocytes derived from psoriasis patients and healthy donors
por: Muhr, P, et al.
Publicado: (2010)

Systematic screening and identification of novel psoriasis-specific genes from the transcriptome of psoriasis-like keratinocytes
por: Wang, Zhen, et al.
Publicado: (2019)

CCN1 promotes IL-1β production in keratinocytes by activating p38 MAPK signaling in psoriasis
por: Sun, Yue, et al.
Publicado: (2017)

Psoriasis-Associated Inflammatory Conditions Induce IL-23 mRNA Expression in Normal Human Epidermal Keratinocytes
por: Kelemen, Evelyn, et al.
Publicado: (2022)

Enhanced Migratory Ability of Neutrophils Toward Epidermis Contributes to the Development of Psoriasis via Crosstalk With Keratinocytes by Releasing IL-17A
por: Liu, Xiu-ting, et al.
Publicado: (2022)

ANGPTL4 Regulates Psoriasis via Modulating Hyperproliferation and Inflammation of Keratinocytes
por: Zuo, Yuyue, et al.
Publicado: (2022)

The Interplay Between Keratinocytes and Immune Cells in the Pathogenesis of Psoriasis
por: Albanesi, Cristina, et al.
Publicado: (2018)

The Effect of Herbal Medicinal Products on Psoriasis-Like Keratinocytes
por: Gendrisch, Fabian, et al.
Publicado: (2021)

SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis
por: Huang, Tao, et al.
Publicado: (2023)

A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4–ERK5 axis
por: Wu, Ling, et al.
Publicado: (2015)

Elevated IL-22 in psoriasis plays an anti-apoptotic role in keratinocytes through mediating Bcl-xL/Bax
por: Wang, Bo, et al.
Publicado: (2020)

Comparative Analysis of Single-Cell Transcriptome Data Reveals a Novel Role of Keratinocyte-Derived IL-23 in Psoriasis
por: Park, Young Joon, et al.
Publicado: (2022)

PG102 Upregulates IL-37 through p38, ERK, and Smad3 Pathways in HaCaT Keratinocytes
por: Kim, Hyun-keun, et al.
Publicado: (2019)

MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9
por: Li, Qingwen, et al.
Publicado: (2022)

C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes
por: Chen, Caifeng, et al.
Publicado: (2018)

Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis
por: Tanigawa, Hiroki, et al.
Publicado: (2016)

Endoplasmic reticulum stress links psoriasis vulgaris with keratinocyte inflammation
por: Zhao, Min, et al.
Publicado: (2020)

Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis
por: Niehues, Hanna, et al.
Publicado: (2021)

IκBζ is a key transcriptional regulator of IL-36–driven psoriasis-related gene expression in keratinocytes
por: Müller, Anne, et al.
Publicado: (2018)

Metformin inhibits IL-1β secretion via impairment of NLRP3 inflammasome in keratinocytes: implications for preventing the development of psoriasis
por: Tsuji, Gaku, et al.
Publicado: (2020)

Label-free electrochemical sensor to investigate the effect of tocopherol on generation of superoxide ions following UV irradiation
por: Gao, Li Xia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_1mg27gnggs4t5kcfmvs1n1hh0v