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Post-traumatic fatal disseminated Apophysomyces elegans infection

Mucorales infections typically occur in immunocompromised hosts. We describe a case of disseminated post-traumatic Apophysomyces elegans in an immunocompetent patient status-post soil inoculation. Fungi introduced at a deep arm laceration leads to neurovascular invasion and dissemination prior to am...

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Detalles Bibliográficos
Autores principales: Egge, Stephanie, Wei, Eric, Clements, Erin, Chandranesan, Andrew Stevenson Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138945/
https://www.ncbi.nlm.nih.gov/pubmed/30225186
http://dx.doi.org/10.1016/j.mmcr.2018.08.002
Descripción
Sumario:Mucorales infections typically occur in immunocompromised hosts. We describe a case of disseminated post-traumatic Apophysomyces elegans in an immunocompetent patient status-post soil inoculation. Fungi introduced at a deep arm laceration leads to neurovascular invasion and dissemination prior to amputation and systemic treatment. We specify strict post-traumatic wound surveillance protocol and roles of novel tissue tests to improve time to diagnosis and prognosis of frequently fatal post-traumatic Mucorales infections.