Phospho-regulation of ATOH1 Is Required for Plasticity of Secretory Progenitors and Tissue Regeneration

The intestinal epithelium is largely maintained by self-renewing stem cells but with apparently committed progenitors also contributing, particularly following tissue damage. However, the mechanism of, and requirement for, progenitor plasticity in mediating pathological response remain unknown. Here...

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Detalles Bibliográficos
Autores principales: Tomic, Goran, Morrissey, Edward, Kozar, Sarah, Ben-Moshe, Shani, Hoyle, Alice, Azzarelli, Roberta, Kemp, Richard, Chilamakuri, Chandra Sekhar Reddy, Itzkovitz, Shalev, Philpott, Anna, Winton, Douglas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138952/
https://www.ncbi.nlm.nih.gov/pubmed/30100168
http://dx.doi.org/10.1016/j.stem.2018.07.002

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