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Checkpoint molecule PD-1-assisted CD8(+) T lymphocyte count in tumor microenvironment predicts overall survival of patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors
PURPOSE: The aim of this study was to determine whether CD8(+) T lymphocyte and its checkpoint-associated module programmed cell death protein 1 (PD-1)/main ligand of PD-1 (PD-L1) pathway impact overall survival (OS) in patients with metastatic renal cell carcinoma (mRCC) treated with tyrosine kinas...
Autores principales: | Yao, Jiaxi, Xi, Wei, Zhu, Yanjun, Wang, Hang, Hu, Xiaoyi, Guo, Jianming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138960/ https://www.ncbi.nlm.nih.gov/pubmed/30237743 http://dx.doi.org/10.2147/CMAR.S172039 |
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