Differential expression analysis of transcriptome data of Trypanosoma brucei RBP6 induction in procyclics leading to infectious metacyclics and bloodstream forms in vitro

We used an in vitro system based on the inducible expression of the RNA binding protein 6 (RBP6) to monitor transcriptome changes during the differentiation of Trypanosoma brucei from non-infectious procyclics to infectious metacyclics and from metacyclics to bloodstream forms. This data file descri...

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Detalles Bibliográficos
Autores principales: Shi, Huafang, Butler, Kiantra, Tschudi, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Biochemistry, Genetics and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139001/
https://www.ncbi.nlm.nih.gov/pubmed/30225310
http://dx.doi.org/10.1016/j.dib.2018.08.169
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author Shi, Huafang
Butler, Kiantra
Tschudi, Christian
author_facet Shi, Huafang
Butler, Kiantra
Tschudi, Christian
author_sort Shi, Huafang
collection PubMed
description We used an in vitro system based on the inducible expression of the RNA binding protein 6 (RBP6) to monitor transcriptome changes during the differentiation of Trypanosoma brucei from non-infectious procyclics to infectious metacyclics and from metacyclics to bloodstream forms. This data file describes the bioinformatics analysis of 20 distinct RNA-Seq samples, with four biological replicates each, highlighting differential transcript abundance. Additional functional annotation analysis using Gene Ontology is also presented. Complete raw data files were deposited at the NCBI Sequence Read Archive – SRA at http://www.ncbi.nlm.nih.gov/Traces/sra/sra.cgi with accession numbers: SRP153824, SRP153562, and SRP152737.
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spelling pubmed-61390012018-09-17 Differential expression analysis of transcriptome data of Trypanosoma brucei RBP6 induction in procyclics leading to infectious metacyclics and bloodstream forms in vitro Shi, Huafang Butler, Kiantra Tschudi, Christian Data Brief Biochemistry, Genetics and Molecular Biology We used an in vitro system based on the inducible expression of the RNA binding protein 6 (RBP6) to monitor transcriptome changes during the differentiation of Trypanosoma brucei from non-infectious procyclics to infectious metacyclics and from metacyclics to bloodstream forms. This data file describes the bioinformatics analysis of 20 distinct RNA-Seq samples, with four biological replicates each, highlighting differential transcript abundance. Additional functional annotation analysis using Gene Ontology is also presented. Complete raw data files were deposited at the NCBI Sequence Read Archive – SRA at http://www.ncbi.nlm.nih.gov/Traces/sra/sra.cgi with accession numbers: SRP153824, SRP153562, and SRP152737. Elsevier 2018-09-01 /pmc/articles/PMC6139001/ /pubmed/30225310 http://dx.doi.org/10.1016/j.dib.2018.08.169 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Biochemistry, Genetics and Molecular Biology
Shi, Huafang
Butler, Kiantra
Tschudi, Christian
Differential expression analysis of transcriptome data of Trypanosoma brucei RBP6 induction in procyclics leading to infectious metacyclics and bloodstream forms in vitro
title Differential expression analysis of transcriptome data of Trypanosoma brucei RBP6 induction in procyclics leading to infectious metacyclics and bloodstream forms in vitro
title_full Differential expression analysis of transcriptome data of Trypanosoma brucei RBP6 induction in procyclics leading to infectious metacyclics and bloodstream forms in vitro
title_fullStr Differential expression analysis of transcriptome data of Trypanosoma brucei RBP6 induction in procyclics leading to infectious metacyclics and bloodstream forms in vitro
title_full_unstemmed Differential expression analysis of transcriptome data of Trypanosoma brucei RBP6 induction in procyclics leading to infectious metacyclics and bloodstream forms in vitro
title_short Differential expression analysis of transcriptome data of Trypanosoma brucei RBP6 induction in procyclics leading to infectious metacyclics and bloodstream forms in vitro
title_sort differential expression analysis of transcriptome data of trypanosoma brucei rbp6 induction in procyclics leading to infectious metacyclics and bloodstream forms in vitro
topic Biochemistry, Genetics and Molecular Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139001/
https://www.ncbi.nlm.nih.gov/pubmed/30225310
http://dx.doi.org/10.1016/j.dib.2018.08.169
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