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Architecture of polymorphisms in the human genome reveals functionally important and positively selected variants in immune response and drug transporter genes

BACKGROUND: Genetic polymorphisms can contribute to phenotypic differences amongst individuals, including disease risk and drug response. Characterization of genetic polymorphisms that modulate gene expression and/or protein function may facilitate the identification of the causal variants. Here, we...

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Detalles Bibliográficos
Autores principales:	Jin, Yu, Wang, Jingbo, Bachtiar, Maulana, Chong, Samuel S., Lee, Caroline G. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139121/ https://www.ncbi.nlm.nih.gov/pubmed/30219098 http://dx.doi.org/10.1186/s40246-018-0175-1

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