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Integration of Genome-Wide DNA Methylation and Transcription Uncovered Aberrant Methylation-Regulated Genes and Pathways in the Peripheral Blood Mononuclear Cells of Systemic Sclerosis

Objective. Systemic sclerosis (SSc) is a systemic connective tissue disease of unknown etiology. Aberrant gene expression and epigenetic modifications in circulating immune cells have been implicated in the pathogenesis of SSc. This study is to delineate the interaction network between gene transcri...

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Detalles Bibliográficos
Autores principales:	Zhu, Honglin, Zhu, Chengsong, Mi, Wentao, Chen, Tao, Zhao, Hongjun, Zuo, Xiaoxia, Luo, Hui, Li, Quan-Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139224/ https://www.ncbi.nlm.nih.gov/pubmed/30245726 http://dx.doi.org/10.1155/2018/7342472

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