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Aqueous Extract of Semen Ziziphi Spinosae Exerts Anxiolytic Effects during Nicotine Withdrawal via Improvement of Amygdaloid CRF/CRF1R Signaling

Anxiety during nicotine withdrawal (NicW) is a key risk factor for smoking relapse. Semen Ziziphi Spinosae (SZS), which is a prototypical hypnotic-sedative herb in Oriental medicine, has been clinically used to treat insomnia and general anxiety disorders for thousands of years. Thus, the present st...

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Detalles Bibliográficos
Autores principales:	Gu, Changhong, Zhao, ZhengLin, Zhu, Xiaodong, Wu, Tong, Lee, Bong Hyo, Jiao, Yu, Lee, Chul Won, Jung, Dae Hwa, Yang, Chae Ha, Zhao, Rongjie, Kim, Sang Chan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139233/ https://www.ncbi.nlm.nih.gov/pubmed/30245730 http://dx.doi.org/10.1155/2018/2419183

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