Cargando…

A DNA Methylation Signature of Addiction in T Cells and Its Reversal With DHEA Intervention

Previous studies in animal models of cocaine craving have delineated broad changes in DNA methylation profiles in the nucleus accumbens. A crucial factor for progress in behavioral and mental health epigenetics is the discovery of epigenetic markers in peripheral tissues. Several studies in primates...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lax, Elad, Warhaftig, Gal, Ohana, David, Maayan, Rachel, Delayahu, Yael, Roska, Paola, Ponizovsky, Alexander M., Weizman, Abraham, Yadid, Gal, Szyf, Moshe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139343/ https://www.ncbi.nlm.nih.gov/pubmed/30250424 http://dx.doi.org/10.3389/fnmol.2018.00322

Ejemplares similares

Novel Opipramol-Baclofen Combination Alleviates Depression and Craving and Facilitates Recovery From Substance Use Disorder—An Animal Model and a Human Study
por: Bareli, Tzofnat, et al.
Publicado: (2021)

Lateral habenula deep brain stimulation for personalized treatment of drug addiction
por: Yadid, Gal, et al.
Publicado: (2013)

Monoamines, BDNF, Dehydroepiandrosterone, DHEA-Sulfate, and Childhood Depression—An Animal Model Study
por: Malkesman, O., et al.
Publicado: (2009)

The methyl donor S-adenosyl methionine reverses the DNA methylation signature of chronic neuropathic pain in mouse frontal cortex
por: Topham, Lucas, et al.
Publicado: (2021)

RNA editing of the 5-HT2C receptor in the central nucleus of the amygdala is involved in resilience behavior
por: Warhaftig, Gal, et al.
Publicado: (2021)

The Effect of Dehydroepiandrosterone Treatment on Neurogenesis, Astrogliosis and Long-Term Cocaine-Seeking Behavior in a Cocaine Self-Administration Model in Rats
por: Ahdoot-Levi, Hadas, et al.
Publicado: (2021)

DNA methylation signatures for breast cancer classification and prognosis
por: Szyf, Moshe
Publicado: (2012)

Shyness discriminates between children with 22q11.2 deletion syndrome and Williams syndrome and predicts emergence of psychosis in 22q11.2 deletion syndrome
por: Schonherz, Yael, et al.
Publicado: (2014)

Conversion of methionine biosynthesis in Escherichia coli from trans- to direct-sulfurylation enhances extracellular methionine levels
por: Gruzdev, Nadya, et al.
Publicado: (2023)

Parental Post-traumatic Stress Disorder Symptoms Are Related to Successful Aging in Offspring of Holocaust Survivors
por: Shrira, Amit, et al.
Publicado: (2017)

In rats, oral oleoyl-DHEA is rapidly hydrolysed and converted to DHEA-sulphate
por: Serrano, Marta, et al.
Publicado: (2007)

Trends in the use of antipsychotics in the Israeli inpatient population, 2004–2013
por: Ponizovsky, Alexander M., et al.
Publicado: (2016)

The transition from acute to chronic pain: dynamic epigenetic reprogramming of the mouse prefrontal cortex up to 1 year after nerve injury
por: Topham, Lucas, et al.
Publicado: (2020)

A SULT2A1 genetic variant identified by GWAS as associated with low serum DHEAS does not impact on the actual DHEA/DHEAS ratio
por: Haring, Robin, et al.
Publicado: (2013)

Examining the Use of Antidepressants for Adolescents with Depression/Anxiety Who Regularly Use Cannabis: A Narrative Review
por: Hen-Shoval, Danielle, et al.
Publicado: (2022)

Cortisol and DHEAS in COVID-19
por: Yavropoulou, Maria P., et al.
Publicado: (2022)

Assessment of DHEAS, cortisol, and DHEAS/cortisol ratio in patients with COVID-19: a pilot study
por: Tomo, Sojit, et al.
Publicado: (2022)

DNA methylation signatures of Prostate Cancer in peripheral T-cells
por: Mehdi, Ali, et al.
Publicado: (2020)

Time-dependence of dehydroepiandrosterone (DHEA), dehydroepiandrosterone-sulfate (DHEAS), and cortisol in survivors and non-survivors of severe sepsis
por: Marx, C, et al.
Publicado: (2002)

Do Dehydroepiandrosterone (DHEA) and Its Sulfate (DHEAS) Play a Role in the Stress Response in Domestic Animals?
por: Gabai, Gianfranco, et al.
Publicado: (2020)

Modulation of Mood States as a Major Factor in Relapse to Substance Use
por: Yadid, Gal, et al.
Publicado: (2012)

The epigenetic signature of chronic pain in the mouse brain
por: Tajerian, Maral, et al.
Publicado: (2014)

DHEAS and Human Development: An Evolutionary Perspective
por: Campbell, Benjamin
Publicado: (2020)

DNA methylation, the early-life social environment and behavioral disorders
por: Szyf, Moshe
Publicado: (2011)

Discovering the Lost Reward: Critical Locations for Endocannabinoid Modulation of the Cortico–Striatal Loop That Are Implicated in Major Depression
por: Goldstein Ferber, Sari, et al.
Publicado: (2021)

Cortisol and DHEA-S levels in pregnant women with severe anxiety
por: Leff-Gelman, Philippe, et al.
Publicado: (2020)

The signature of liver cancer in immune cells DNA methylation
por: Zhang, Yonghong, et al.
Publicado: (2018)

Gestational Diabetes Type 2: Variation in High-Density Lipoproteins Composition and Function
por: Pasternak, Yael, et al.
Publicado: (2020)

Internet addiction: Gender-associated differences in psychological characteristics
por: Ponizovsky, P., et al.
Publicado: (2022)

Dehydroepiandrosterone (DHEA) Serum Levels Indicate Cerebrospinal Fluid Levels of DHEA and Estradiol (E2) in Women at Term Pregnancy
por: Habib, Pardes, et al.
Publicado: (2021)

Chronic Depression Alters Mothers’ DHEA and DEHA-to-Cortisol Ratio: Implications for Maternal Behavior and Child Outcomes
por: Apter-Levy, Yael, et al.
Publicado: (2020)

Discovery and characterization of small molecule inhibitors of cystathionine gamma‐synthase with in planta activity
por: Bloch, Itai, et al.
Publicado: (2021)

Cascade biotransformation of dehydroepiandrosterone (DHEA) by Beauveria species
por: Kozłowska, Ewa, et al.
Publicado: (2018)

Sensory Arsenal on the Stinger of the Parasitoid Jewel Wasp and Its Possible Role in Identifying Cockroach Brains
por: Gal, Ram, et al.
Publicado: (2014)

Effect of Vitamin D Status on Von Willebrand Factor and ADAMTS13 in Diabetic Patients on Chronic Hemodialysis
por: Cohen-Hagai, Keren, et al.
Publicado: (2017)

Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1
por: Mueller, Jonathan W., et al.
Publicado: (2018)

Placenta-Derived Mesenchymal-like Adherent Stromal Cells as an Effective Cell Therapy for Cocaine Addiction in a Rat Model
por: Pe’er-Nissan, Hilla, et al.
Publicado: (2022)

DNA methylation signatures of breast cancer in peripheral T-cells
por: Parashar, Surabhi, et al.
Publicado: (2018)

Social rank-associated stress vulnerability predisposes individuals to cocaine attraction
por: Yanovich, Chen, et al.
Publicado: (2018)

Modulation of PARP-1 Activity in a Broad Time Window Attenuates Memorizing Fear
por: Elharrar, Einat, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6gohh8t6jnvr0iipc58b570emi