Coagulation Factor Plasma Levels Following Administration of a 4-Factor Prothrombin Complex Concentrate for Rapid Vitamin K Antagonist Reversal in Japanese Patients

BACKGROUND: Four-factor prothrombin complex concentrates (4F-PCCs) have been approved for urgent vitamin K antagonist reversal in Western countries for many years. Ethnicity and genetic variations between populations may influence the pharmacokinetic profile of 4F-PCC treatments. OBJECTIVE: To repor...

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Detalles Bibliográficos
Autores principales: Yasaka, Masahiro, Brainsky, Andres, Zhang, Peijin, Kushimoto, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139595/
https://www.ncbi.nlm.nih.gov/pubmed/30224939
http://dx.doi.org/10.1016/j.curtheres.2018.08.001

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