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Crowding and Pausing Strongly Affect Dynamics of Kinesin-1 Motors along Microtubules

Molecular motors of the kinesin-1 family move in a directed and processive fashion along microtubules. It is generally accepted that steric hindrance of motors leads to crowding effects; however, little is known about the specific interactions involved. We employ an agent-based lattice gas model to...

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Detalles Bibliográficos
Autores principales: Rank, Matthias, Frey, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139881/
https://www.ncbi.nlm.nih.gov/pubmed/30146266
http://dx.doi.org/10.1016/j.bpj.2018.07.017