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Crowding and Pausing Strongly Affect Dynamics of Kinesin-1 Motors along Microtubules
Molecular motors of the kinesin-1 family move in a directed and processive fashion along microtubules. It is generally accepted that steric hindrance of motors leads to crowding effects; however, little is known about the specific interactions involved. We employ an agent-based lattice gas model to...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139881/ https://www.ncbi.nlm.nih.gov/pubmed/30146266 http://dx.doi.org/10.1016/j.bpj.2018.07.017 |