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Computational Model of Chimeric Antigen Receptors Explains Site-Specific Phosphorylation Kinetics
Chimeric antigen receptors (CARs) have recently been approved for the treatment of hematological malignancies, but our lack of understanding of the basic mechanisms that activate these proteins has made it difficult to optimize and control CAR-based therapies. In this study, we use phosphoproteomic...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139883/ https://www.ncbi.nlm.nih.gov/pubmed/30197180 http://dx.doi.org/10.1016/j.bpj.2018.08.018 |