Meeting report, ICH M7 relevant workshop: use of (Q)SAR systems and expert judgment

Use of Quantitative Structure-Activity Relationships ((Q)SAR) prediction tools has been increasing since the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) M7 guideline was issued in June 2014. The Japanese Environmental Mutagen Society and...

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Autores principales: Mishima, Masayuki, Hashizume, Tsuneo, Haranosono, Yu, Nagato, Yusuke, Takeshita, Kentaro, Fukuchi, Junichi, Homma, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Meeting Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139937/
http://dx.doi.org/10.1186/s41021-018-0107-2
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author Mishima, Masayuki
Hashizume, Tsuneo
Haranosono, Yu
Nagato, Yusuke
Takeshita, Kentaro
Fukuchi, Junichi
Homma, Masamitsu
author_facet Mishima, Masayuki
Hashizume, Tsuneo
Haranosono, Yu
Nagato, Yusuke
Takeshita, Kentaro
Fukuchi, Junichi
Homma, Masamitsu
author_sort Mishima, Masayuki
collection PubMed
description Use of Quantitative Structure-Activity Relationships ((Q)SAR) prediction tools has been increasing since the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) M7 guideline was issued in June 2014. The Japanese Environmental Mutagen Society and the Bacterial Mutagenicity Study Group took the initiative of the workshop on (Q)SAR in 2016 to discuss using (Q)SAR to predict mutagenicity. The aim of the workshop was to form a common understanding on the current use of (Q)SAR tools in industry and for regulatory purposes and on the process of expert judgment. This report summarizes the general session that reviewed the use of (Q)SAR tools and the case study session that discussed expert judgment.
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spelling pubmed-61399372018-09-20 Meeting report, ICH M7 relevant workshop: use of (Q)SAR systems and expert judgment Mishima, Masayuki Hashizume, Tsuneo Haranosono, Yu Nagato, Yusuke Takeshita, Kentaro Fukuchi, Junichi Homma, Masamitsu Genes Environ Meeting Report Use of Quantitative Structure-Activity Relationships ((Q)SAR) prediction tools has been increasing since the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) M7 guideline was issued in June 2014. The Japanese Environmental Mutagen Society and the Bacterial Mutagenicity Study Group took the initiative of the workshop on (Q)SAR in 2016 to discuss using (Q)SAR to predict mutagenicity. The aim of the workshop was to form a common understanding on the current use of (Q)SAR tools in industry and for regulatory purposes and on the process of expert judgment. This report summarizes the general session that reviewed the use of (Q)SAR tools and the case study session that discussed expert judgment. BioMed Central 2018-09-17 /pmc/articles/PMC6139937/ http://dx.doi.org/10.1186/s41021-018-0107-2 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Meeting Report
Mishima, Masayuki
Hashizume, Tsuneo
Haranosono, Yu
Nagato, Yusuke
Takeshita, Kentaro
Fukuchi, Junichi
Homma, Masamitsu
Meeting report, ICH M7 relevant workshop: use of (Q)SAR systems and expert judgment
title Meeting report, ICH M7 relevant workshop: use of (Q)SAR systems and expert judgment
title_full Meeting report, ICH M7 relevant workshop: use of (Q)SAR systems and expert judgment
title_fullStr Meeting report, ICH M7 relevant workshop: use of (Q)SAR systems and expert judgment
title_full_unstemmed Meeting report, ICH M7 relevant workshop: use of (Q)SAR systems and expert judgment
title_short Meeting report, ICH M7 relevant workshop: use of (Q)SAR systems and expert judgment
title_sort meeting report, ich m7 relevant workshop: use of (q)sar systems and expert judgment
topic Meeting Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139937/
http://dx.doi.org/10.1186/s41021-018-0107-2
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