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The Nogo Receptor Ligand LGI1 Regulates Synapse Number and Synaptic Activity in Hippocampal and Cortical Neurons

Leucine-rich glioma-inactivated protein 1 (LGI1) is a secreted neuronal protein and a Nogo receptor 1 (NgR1) ligand. Mutations in LGI1 in humans causes autosomal dominant lateral temporal lobe epilepsy and homozygous deletion of LGI1 in mice results in severe epileptic seizures that cause early post...

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Detalles Bibliográficos
Autores principales:	Thomas, Rhalena A., Gibon, Julien, Chen, Carol X. Q., Chierzi, Sabrina, Soubannier, Vincent G., Baulac, Stephanie, Séguéla, Philippe, Murai, Keith, Barker, Philip A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2018
Materias:	New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140115/ https://www.ncbi.nlm.nih.gov/pubmed/30225353 http://dx.doi.org/10.1523/ENEURO.0185-18.2018

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