Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials

We present data derived from an exposure experiment in which three cell-lines representative of cell types of the respiratory tissue (epithelial type-I A549, epithelial type-II BEAS-2B, and macrophage THP-1) have been exposed to ten different carbon-based nanomaterials for 48 h. In particular, we pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Scala, Giovanni, Marwah, Veer, Kinaret, Pia, Sund, Jukka, Fortino, Vittorio, Greco, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Environmental Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140287/
https://www.ncbi.nlm.nih.gov/pubmed/30228994
http://dx.doi.org/10.1016/j.dib.2018.05.107
Descripción
Sumario:We present data derived from an exposure experiment in which three cell-lines representative of cell types of the respiratory tissue (epithelial type-I A549, epithelial type-II BEAS-2B, and macrophage THP-1) have been exposed to ten different carbon-based nanomaterials for 48 h. In particular, we provide: genome-wide mRNA and miRNA expression, and DNA methylation; gene tables, containing information on the aberrations induced in these three genomic data layers at the gene level; mechanism of action (MOA) maps representing the comparative functional alteration induced in each cell line and each exposure.

Ejemplares similares