Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials

We present data derived from an exposure experiment in which three cell-lines representative of cell types of the respiratory tissue (epithelial type-I A549, epithelial type-II BEAS-2B, and macrophage THP-1) have been exposed to ten different carbon-based nanomaterials for 48 h. In particular, we pr...

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Autores principales: Scala, Giovanni, Marwah, Veer, Kinaret, Pia, Sund, Jukka, Fortino, Vittorio, Greco, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Environmental Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140287/
https://www.ncbi.nlm.nih.gov/pubmed/30228994
http://dx.doi.org/10.1016/j.dib.2018.05.107
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author Scala, Giovanni
Marwah, Veer
Kinaret, Pia
Sund, Jukka
Fortino, Vittorio
Greco, Dario
author_facet Scala, Giovanni
Marwah, Veer
Kinaret, Pia
Sund, Jukka
Fortino, Vittorio
Greco, Dario
author_sort Scala, Giovanni
collection PubMed
description We present data derived from an exposure experiment in which three cell-lines representative of cell types of the respiratory tissue (epithelial type-I A549, epithelial type-II BEAS-2B, and macrophage THP-1) have been exposed to ten different carbon-based nanomaterials for 48 h. In particular, we provide: genome-wide mRNA and miRNA expression, and DNA methylation; gene tables, containing information on the aberrations induced in these three genomic data layers at the gene level; mechanism of action (MOA) maps representing the comparative functional alteration induced in each cell line and each exposure.
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spelling pubmed-61402872018-09-18 Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials Scala, Giovanni Marwah, Veer Kinaret, Pia Sund, Jukka Fortino, Vittorio Greco, Dario Data Brief Environmental Science We present data derived from an exposure experiment in which three cell-lines representative of cell types of the respiratory tissue (epithelial type-I A549, epithelial type-II BEAS-2B, and macrophage THP-1) have been exposed to ten different carbon-based nanomaterials for 48 h. In particular, we provide: genome-wide mRNA and miRNA expression, and DNA methylation; gene tables, containing information on the aberrations induced in these three genomic data layers at the gene level; mechanism of action (MOA) maps representing the comparative functional alteration induced in each cell line and each exposure. Elsevier 2018-05-25 /pmc/articles/PMC6140287/ /pubmed/30228994 http://dx.doi.org/10.1016/j.dib.2018.05.107 Text en © 2018 Published by Elsevier Inc. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Environmental Science
Scala, Giovanni
Marwah, Veer
Kinaret, Pia
Sund, Jukka
Fortino, Vittorio
Greco, Dario
Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials
title Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials
title_full Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials
title_fullStr Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials
title_full_unstemmed Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials
title_short Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials
title_sort integration of genome-wide mrna and mirna expression, and dna methylation data of three cell lines exposed to ten carbon nanomaterials
topic Environmental Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140287/
https://www.ncbi.nlm.nih.gov/pubmed/30228994
http://dx.doi.org/10.1016/j.dib.2018.05.107
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