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The unusual flagellar-targeting mechanism and functions of the trypanosome ortholog of the ciliary GTPase Arl13b

The small GTPase Arl13b is one of the most conserved and ancient ciliary proteins. In human and animals, Arl13b is primarily associated with the ciliary membrane, where it acts as a guanine-nucleotide-exchange factor (GEF) for Arl3 and is implicated in a variety of ciliary and cellular functions. We...

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Detalles Bibliográficos
Autores principales: Zhang, Yiliu, Huang, Yameng, Srivathsan, Amrita, Lim, Teck Kwang, Lin, Qingsong, He, Cynthia Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140319/
https://www.ncbi.nlm.nih.gov/pubmed/30097558
http://dx.doi.org/10.1242/jcs.219071