PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival

Glioblastoma multiforme (GBM) is the most common type of malignant brain tumors in adults and has a dismal prognosis. The highly aggressive invasion of malignant cells into the normal brain parenchyma renders complete surgical resection of GBM tumors impossible, increases resistance to therapeutic t...

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Detalles Bibliográficos
Autores principales: Ding, Zonghui, Dhruv, Harshil, Kwiatkowska-Piwowarczyk, Aneta, Ruggieri, Rosamaria, Kloss, Jean, Symons, Marc, Pirrotte, Patrick, Eschbacher, Jennifer M., Tran, Nhan L., Loftus, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140379/
https://www.ncbi.nlm.nih.gov/pubmed/30219706
http://dx.doi.org/10.1016/j.neo.2018.08.008

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