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Structure of a patient-derived antibody in complex with allergen reveals simultaneous conventional and superantigen-like recognition
Antibodies classically bind antigens via their complementarity-determining regions, but an alternative mode of interaction involving V-domain framework regions has been observed for some B cell “superantigens.” We report the crystal structure of an antibody employing both modes of interaction simult...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140506/ https://www.ncbi.nlm.nih.gov/pubmed/30150373 http://dx.doi.org/10.1073/pnas.1806840115 |