Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody

The P2X7 channel is involved in the pathogenesis of various CNS diseases. An increasing number of studies suggest its presence in neurons where its putative functions remain controversial for more than a decade. To resolve this issue and to provide a model for analysis of P2X7 functions, we generate...

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Detalles Bibliográficos
Autores principales: Kaczmarek-Hajek, Karina, Zhang, Jiong, Kopp, Robin, Grosche, Antje, Rissiek, Björn, Saul, Anika, Bruzzone, Santina, Engel, Tobias, Jooss, Tina, Krautloher, Anna, Schuster, Stefanie, Magnus, Tim, Stadelmann, Christine, Sirko, Swetlana, Koch-Nolte, Friedrich, Eulenburg, Volker, Nicke, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140716/
https://www.ncbi.nlm.nih.gov/pubmed/30074479
http://dx.doi.org/10.7554/eLife.36217

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