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Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles
DNA methylation is recognized as one of several epigenetic regulators of gene expression and as potential driver of carcinogenesis through gene-silencing of tumor suppressors and activation of oncogenes. However, abnormal methylation, even of promoter regions, does not necessarily alter gene express...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140810/ https://www.ncbi.nlm.nih.gov/pubmed/29697014 http://dx.doi.org/10.1080/15592294.2018.1460034 |