Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles

DNA methylation is recognized as one of several epigenetic regulators of gene expression and as potential driver of carcinogenesis through gene-silencing of tumor suppressors and activation of oncogenes. However, abnormal methylation, even of promoter regions, does not necessarily alter gene express...

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Detalles Bibliográficos
Autores principales: Klett, Hagen, Balavarca, Yesilda, Toth, Reka, Gigic, Biljana, Habermann, Nina, Scherer, Dominique, Schrotz-King, Petra, Ulrich, Alexis, Schirmacher, Peter, Herpel, Esther, Brenner, Hermann, Ulrich, Cornelia M., Michels, Karin B., Busch, Hauke, Boerries, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140810/
https://www.ncbi.nlm.nih.gov/pubmed/29697014
http://dx.doi.org/10.1080/15592294.2018.1460034

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