Epigenetics of gastrointestinal diseases: notes from a workshop

International experts gathered at the Mayo Clinic (Rochester MN, USA) on February 27th-28th, 2017 for a meeting entitled ‘Basic and Translational Facets of the Epigenetics of GI Diseases’. This workshop summarized recent advances on the role of epigenetics in the pathobiology of gastrointestinal (GI...

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Detalles Bibliográficos
Autores principales: Marks, David L., Olson, Rachel L., Urrutia, Raul, Billadeau, Daniel D., Roy, Nilotpal, Calin, George A., Fabbri, Muller, Koutsioumpa, Marina, Iliopoulos, Dimitrios, Ordog, Tamas, Huebert, Robert, Sarmento, Olga, Bamidele, Adebowale O., Faubion, William, Lomberk, Gwen L., Siveke, Jens, Ahuja, Nita, Iovanna, Juan, Hlady, Ryan A., Robertson, Keith, Kisiel, John, Pin, Christopher L., Fernandez-Zapico, Martin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Meeting Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140811/
https://www.ncbi.nlm.nih.gov/pubmed/30056798
http://dx.doi.org/10.1080/15592294.2018.1464351
Descripción
Sumario:International experts gathered at the Mayo Clinic (Rochester MN, USA) on February 27th-28th, 2017 for a meeting entitled ‘Basic and Translational Facets of the Epigenetics of GI Diseases’. This workshop summarized recent advances on the role of epigenetics in the pathobiology of gastrointestinal (GI) diseases. Highlights of the meeting included recent advances on the involvement of different epigenetic mechanisms in malignant and nonmalignant GI disorders and the epigenetic heterogeneity exhibited in these diseases. The translational value of epigenetic drugs, as well as the current and future use of epigenetic changes (i.e., DNA methylation patterns) as biomarkers for early detection tools or disease stratification were also important topics of discussion.

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