Cargando…

Evaluation of coated steroidal implants containing trenbolone acetate and estradiol-17β on live performance, carcass traits, and sera metabolites in finishing steers

Crossbred beef steers (n = 240; 12 pens/treatment; initial BW = 305 ± 17.7 kg) were used in a randomized block design feedlot study to evaluate the influence of coated trenbolone acetate (TBA) and estradiol-17β (E(2)) implants (Merck Animal Health, Madison, NJ) on gain performance, carcass traits, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Zachary K, Thompson, Alex J, Hutcheson, John P, Nichols, Wade T, Johnson, Bradley J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140838/
https://www.ncbi.nlm.nih.gov/pubmed/29534183
http://dx.doi.org/10.1093/jas/sky095
_version_ 1783355632776118272
author Smith, Zachary K
Thompson, Alex J
Hutcheson, John P
Nichols, Wade T
Johnson, Bradley J
author_facet Smith, Zachary K
Thompson, Alex J
Hutcheson, John P
Nichols, Wade T
Johnson, Bradley J
author_sort Smith, Zachary K
collection PubMed
description Crossbred beef steers (n = 240; 12 pens/treatment; initial BW = 305 ± 17.7 kg) were used in a randomized block design feedlot study to evaluate the influence of coated trenbolone acetate (TBA) and estradiol-17β (E(2)) implants (Merck Animal Health, Madison, NJ) on gain performance, carcass traits, and sera metabolites. The five treatments were no implant (NI), Revalor-XR on d 0 [200 mg TBA + 20 mg E(2) (coated); XR], Revalor-XS on d 0 [200 mg TBA + 40 mg E(2) (total): 80 mg TBA + 16 mg E(2) (noncoated) and 120 mg TBA + 24 mg E(2) (coated); XS], Revalor-200 on d 0 [200 mg TBA + 20 mg E(2) (noncoated); E200], or Revalor-200 on d 70 (D200). Interim BW and blood were collected on d 0, 14, 35, 70, 105, 140, and 175 prior to feeding and on d 213 prior to shipping. Following a 24 h clot at 4 °C, sera was harvested to quantify circulating E(2), IGF-I, NEFA, serum urea-N (SUN), and 17β-trenbolone (17β-TbOH). Implanted steers had greater (P ≤ 0.05) ADG, G:F, and final BW than NI controls. Implants increased (P < 0.05) HCW by 8%, 366 vs. 391, 414, 380, and 396 ± 6.4 kg, for NI vs. XR, XS, E200, and D200, respectively. The greatest (P ≤ 0.05) dressing percentage, yield grade, and calculated empty body fat occurred in XS, which had greater (P < 0.05) rib fat than NI, XR, and D200. Marbling scores in NI were greater (P < 0.05) than E200 and D200; steers in XR and XS were intermediate (P > 0.10), not differing from NI, E200, or D200. An implant × day interaction (P ≤ 0.01) was noted for circulating E(2), IGF-I, SUN, and 17β-TbOH. Implanted steers had elevated (P ≤ 0.05) sera E(2), IGF-I, and 17β-TbOH, and decreased (P < 0.05) SUN following implantation compared to NI controls. Serum NEFA differed (P < 0.01) over time, but did not differ (P > 0.10) due to implant treatment. These data indicated that the polymer coating applied to the XR implant delayed release of steroidal hormones congruently to D200, with no negative impact on marbling. The greatest dose of E(2), contained in XS, provided improvements in gain and carcass weight without detriment to marbling scores compared to NI.
format Online
Article
Text
id pubmed-6140838
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-61408382018-10-11 Evaluation of coated steroidal implants containing trenbolone acetate and estradiol-17β on live performance, carcass traits, and sera metabolites in finishing steers Smith, Zachary K Thompson, Alex J Hutcheson, John P Nichols, Wade T Johnson, Bradley J J Anim Sci Growth Biology Crossbred beef steers (n = 240; 12 pens/treatment; initial BW = 305 ± 17.7 kg) were used in a randomized block design feedlot study to evaluate the influence of coated trenbolone acetate (TBA) and estradiol-17β (E(2)) implants (Merck Animal Health, Madison, NJ) on gain performance, carcass traits, and sera metabolites. The five treatments were no implant (NI), Revalor-XR on d 0 [200 mg TBA + 20 mg E(2) (coated); XR], Revalor-XS on d 0 [200 mg TBA + 40 mg E(2) (total): 80 mg TBA + 16 mg E(2) (noncoated) and 120 mg TBA + 24 mg E(2) (coated); XS], Revalor-200 on d 0 [200 mg TBA + 20 mg E(2) (noncoated); E200], or Revalor-200 on d 70 (D200). Interim BW and blood were collected on d 0, 14, 35, 70, 105, 140, and 175 prior to feeding and on d 213 prior to shipping. Following a 24 h clot at 4 °C, sera was harvested to quantify circulating E(2), IGF-I, NEFA, serum urea-N (SUN), and 17β-trenbolone (17β-TbOH). Implanted steers had greater (P ≤ 0.05) ADG, G:F, and final BW than NI controls. Implants increased (P < 0.05) HCW by 8%, 366 vs. 391, 414, 380, and 396 ± 6.4 kg, for NI vs. XR, XS, E200, and D200, respectively. The greatest (P ≤ 0.05) dressing percentage, yield grade, and calculated empty body fat occurred in XS, which had greater (P < 0.05) rib fat than NI, XR, and D200. Marbling scores in NI were greater (P < 0.05) than E200 and D200; steers in XR and XS were intermediate (P > 0.10), not differing from NI, E200, or D200. An implant × day interaction (P ≤ 0.01) was noted for circulating E(2), IGF-I, SUN, and 17β-TbOH. Implanted steers had elevated (P ≤ 0.05) sera E(2), IGF-I, and 17β-TbOH, and decreased (P < 0.05) SUN following implantation compared to NI controls. Serum NEFA differed (P < 0.01) over time, but did not differ (P > 0.10) due to implant treatment. These data indicated that the polymer coating applied to the XR implant delayed release of steroidal hormones congruently to D200, with no negative impact on marbling. The greatest dose of E(2), contained in XS, provided improvements in gain and carcass weight without detriment to marbling scores compared to NI. Oxford University Press 2018-05 2018-03-09 /pmc/articles/PMC6140838/ /pubmed/29534183 http://dx.doi.org/10.1093/jas/sky095 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of the American Society of Animal Science. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Growth Biology
Smith, Zachary K
Thompson, Alex J
Hutcheson, John P
Nichols, Wade T
Johnson, Bradley J
Evaluation of coated steroidal implants containing trenbolone acetate and estradiol-17β on live performance, carcass traits, and sera metabolites in finishing steers
title Evaluation of coated steroidal implants containing trenbolone acetate and estradiol-17β on live performance, carcass traits, and sera metabolites in finishing steers
title_full Evaluation of coated steroidal implants containing trenbolone acetate and estradiol-17β on live performance, carcass traits, and sera metabolites in finishing steers
title_fullStr Evaluation of coated steroidal implants containing trenbolone acetate and estradiol-17β on live performance, carcass traits, and sera metabolites in finishing steers
title_full_unstemmed Evaluation of coated steroidal implants containing trenbolone acetate and estradiol-17β on live performance, carcass traits, and sera metabolites in finishing steers
title_short Evaluation of coated steroidal implants containing trenbolone acetate and estradiol-17β on live performance, carcass traits, and sera metabolites in finishing steers
title_sort evaluation of coated steroidal implants containing trenbolone acetate and estradiol-17β on live performance, carcass traits, and sera metabolites in finishing steers
topic Growth Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140838/
https://www.ncbi.nlm.nih.gov/pubmed/29534183
http://dx.doi.org/10.1093/jas/sky095
work_keys_str_mv AT smithzacharyk evaluationofcoatedsteroidalimplantscontainingtrenboloneacetateandestradiol17bonliveperformancecarcasstraitsandserametabolitesinfinishingsteers
AT thompsonalexj evaluationofcoatedsteroidalimplantscontainingtrenboloneacetateandestradiol17bonliveperformancecarcasstraitsandserametabolitesinfinishingsteers
AT hutchesonjohnp evaluationofcoatedsteroidalimplantscontainingtrenboloneacetateandestradiol17bonliveperformancecarcasstraitsandserametabolitesinfinishingsteers
AT nicholswadet evaluationofcoatedsteroidalimplantscontainingtrenboloneacetateandestradiol17bonliveperformancecarcasstraitsandserametabolitesinfinishingsteers
AT johnsonbradleyj evaluationofcoatedsteroidalimplantscontainingtrenboloneacetateandestradiol17bonliveperformancecarcasstraitsandserametabolitesinfinishingsteers