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Saikosaponin A modulates remodeling of Kv4.2-mediated A-type voltage-gated potassium currents in rat chronic temporal lobe epilepsy

BACKGROUND: Chronic temporal lobe epilepsy (cTLE) is the most common intractable epilepsy. Recent studies have shown that saikosaponin A (SSa) could inhibit epileptiform discharges induced by 4 action potentials and selectively increase the transient inactivating K(+) currents (I(A)). However, the m...

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Detalles Bibliográficos
Autores principales:	Hong, Yu, Deng, Ning, Jin, Han-Na, Xuan, Zheng-Zheng, Qian, Yi-Xiao, Wu, Zhi-yong, Xie, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141107/ https://www.ncbi.nlm.nih.gov/pubmed/30254424 http://dx.doi.org/10.2147/DDDT.S166408

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