FBXW2 localizes with osteocalcin in bovine periosteum on culture dishes as visualized by double immunostaining

Osteocalcin (OC) is a well-known protein related to bone, however, the role of F-box and WD-40 domain-containing protein 2 (FBXW2) in bone remains unclear. In 2016, the presence of FBXW2 in bovine periosteum was reported. In this study, double immunostaining was used to investigate the relationship...

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Detalles Bibliográficos
Autor principal: Akiyama, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141272/
https://www.ncbi.nlm.nih.gov/pubmed/30229138
http://dx.doi.org/10.1016/j.heliyon.2018.e00782
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author Akiyama, Mari
author_facet Akiyama, Mari
author_sort Akiyama, Mari
collection PubMed
description Osteocalcin (OC) is a well-known protein related to bone, however, the role of F-box and WD-40 domain-containing protein 2 (FBXW2) in bone remains unclear. In 2016, the presence of FBXW2 in bovine periosteum was reported. In this study, double immunostaining was used to investigate the relationship between OC and FBXW2. FBXW2 showed tubular structures, and OC showed a similar localization pattern as FBXW2. Double immunostaining findings suggested that FBXW2 tubes were coated with OC. To the author's knowledge, this is the first study to reveal the interaction between OC and FBXW2.
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spelling pubmed-61412722018-09-18 FBXW2 localizes with osteocalcin in bovine periosteum on culture dishes as visualized by double immunostaining Akiyama, Mari Heliyon Article Osteocalcin (OC) is a well-known protein related to bone, however, the role of F-box and WD-40 domain-containing protein 2 (FBXW2) in bone remains unclear. In 2016, the presence of FBXW2 in bovine periosteum was reported. In this study, double immunostaining was used to investigate the relationship between OC and FBXW2. FBXW2 showed tubular structures, and OC showed a similar localization pattern as FBXW2. Double immunostaining findings suggested that FBXW2 tubes were coated with OC. To the author's knowledge, this is the first study to reveal the interaction between OC and FBXW2. Elsevier 2018-09-14 /pmc/articles/PMC6141272/ /pubmed/30229138 http://dx.doi.org/10.1016/j.heliyon.2018.e00782 Text en © 2018 The Author http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Akiyama, Mari
FBXW2 localizes with osteocalcin in bovine periosteum on culture dishes as visualized by double immunostaining
title FBXW2 localizes with osteocalcin in bovine periosteum on culture dishes as visualized by double immunostaining
title_full FBXW2 localizes with osteocalcin in bovine periosteum on culture dishes as visualized by double immunostaining
title_fullStr FBXW2 localizes with osteocalcin in bovine periosteum on culture dishes as visualized by double immunostaining
title_full_unstemmed FBXW2 localizes with osteocalcin in bovine periosteum on culture dishes as visualized by double immunostaining
title_short FBXW2 localizes with osteocalcin in bovine periosteum on culture dishes as visualized by double immunostaining
title_sort fbxw2 localizes with osteocalcin in bovine periosteum on culture dishes as visualized by double immunostaining
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141272/
https://www.ncbi.nlm.nih.gov/pubmed/30229138
http://dx.doi.org/10.1016/j.heliyon.2018.e00782
work_keys_str_mv AT akiyamamari fbxw2localizeswithosteocalcininbovineperiosteumonculturedishesasvisualizedbydoubleimmunostaining

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