HPLC-ESI-MS method for C(60) fullerene mitochondrial content quantification

The presented dataset describes the quantification of carbon nanoparticle C(60) fullerene accumulated in mitochondria of human leukemic cells treated with nanostructure. Firstly, the high performance liquid chromatography–electro spray ionization–mass spectrometry (HPLC-ESI-MS) method was developed...

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Detalles Bibliográficos
Autores principales: Grebinyk, Anna, Grebinyk, Sergii, Prylutska, Svitlana, Ritter, Uwe, Matyshevska, Olga, Dandekar, Thomas, Frohme, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Medicine and Dentistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141383/
https://www.ncbi.nlm.nih.gov/pubmed/30229080
http://dx.doi.org/10.1016/j.dib.2018.06.089
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author Grebinyk, Anna
Grebinyk, Sergii
Prylutska, Svitlana
Ritter, Uwe
Matyshevska, Olga
Dandekar, Thomas
Frohme, Marcus
author_facet Grebinyk, Anna
Grebinyk, Sergii
Prylutska, Svitlana
Ritter, Uwe
Matyshevska, Olga
Dandekar, Thomas
Frohme, Marcus
author_sort Grebinyk, Anna
collection PubMed
description The presented dataset describes the quantification of carbon nanoparticle C(60) fullerene accumulated in mitochondria of human leukemic cells treated with nanostructure. Firstly, the high performance liquid chromatography–electro spray ionization–mass spectrometry (HPLC-ESI-MS) method was developed for quantitative analysis of pristine C(60) fullerene. Then, human leukemic cells were incubated with C(60) fullerene, homogenized and subjected to the differential centrifugation to retrieve mitochondrial fraction. The C(60) fullerene content was quantified by HPLC-ESI-MS in extracts of cellular fractions. This data article refers to the research article “C(60) Fullerene Accumulation in Human Leukemic Cells and Perspectives of LED-mediated Photodynamic Therapy” by Grebinyk et al. [1].
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spelling pubmed-61413832018-09-18 HPLC-ESI-MS method for C(60) fullerene mitochondrial content quantification Grebinyk, Anna Grebinyk, Sergii Prylutska, Svitlana Ritter, Uwe Matyshevska, Olga Dandekar, Thomas Frohme, Marcus Data Brief Medicine and Dentistry The presented dataset describes the quantification of carbon nanoparticle C(60) fullerene accumulated in mitochondria of human leukemic cells treated with nanostructure. Firstly, the high performance liquid chromatography–electro spray ionization–mass spectrometry (HPLC-ESI-MS) method was developed for quantitative analysis of pristine C(60) fullerene. Then, human leukemic cells were incubated with C(60) fullerene, homogenized and subjected to the differential centrifugation to retrieve mitochondrial fraction. The C(60) fullerene content was quantified by HPLC-ESI-MS in extracts of cellular fractions. This data article refers to the research article “C(60) Fullerene Accumulation in Human Leukemic Cells and Perspectives of LED-mediated Photodynamic Therapy” by Grebinyk et al. [1]. Elsevier 2018-07-10 /pmc/articles/PMC6141383/ /pubmed/30229080 http://dx.doi.org/10.1016/j.dib.2018.06.089 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Medicine and Dentistry
Grebinyk, Anna
Grebinyk, Sergii
Prylutska, Svitlana
Ritter, Uwe
Matyshevska, Olga
Dandekar, Thomas
Frohme, Marcus
HPLC-ESI-MS method for C(60) fullerene mitochondrial content quantification
title HPLC-ESI-MS method for C(60) fullerene mitochondrial content quantification
title_full HPLC-ESI-MS method for C(60) fullerene mitochondrial content quantification
title_fullStr HPLC-ESI-MS method for C(60) fullerene mitochondrial content quantification
title_full_unstemmed HPLC-ESI-MS method for C(60) fullerene mitochondrial content quantification
title_short HPLC-ESI-MS method for C(60) fullerene mitochondrial content quantification
title_sort hplc-esi-ms method for c(60) fullerene mitochondrial content quantification
topic Medicine and Dentistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141383/
https://www.ncbi.nlm.nih.gov/pubmed/30229080
http://dx.doi.org/10.1016/j.dib.2018.06.089
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