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Shape transformable bifurcated stents
Non-invasive delivery of artificial implants, stents or devices in patients is vital for rapid and successful recovery. Unfortunately, because the delivery passage is often narrower than the size of the delivered object, a compromise between the shape that is effective at the targeted location and a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141457/ https://www.ncbi.nlm.nih.gov/pubmed/30224641 http://dx.doi.org/10.1038/s41598-018-32129-3 |
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author | Kim, Taeyoung Lee, Yong-Gu |
author_facet | Kim, Taeyoung Lee, Yong-Gu |
author_sort | Kim, Taeyoung |
collection | PubMed |
description | Non-invasive delivery of artificial implants, stents or devices in patients is vital for rapid and successful recovery. Unfortunately, because the delivery passage is often narrower than the size of the delivered object, a compromise between the shape that is effective at the targeted location and a thin form that allows smooth unobstructed travel to the destination is needed. We address this problem through two key technologies: 3D printing and shape memory polymers (SMPs). 3D printing can produce patient-customizable objects, and SMPs can change their initially formed shape to the final desired shape through external stimulation. Using these two technologies, we examine the design and fabrication of bifurcated stents. This study presents a mock-up where blood vessels are fabricated using moulded silicon, which supports the effectiveness of the proposed method. The experimental results reveal that a bifurcated stent with a kirigami structure can smoothly travel inside a vessel without being obstructed by branched parts. We believe that this work can improve the success rate of stent insertion operations in medicine. |
format | Online Article Text |
id | pubmed-6141457 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-61414572018-09-20 Shape transformable bifurcated stents Kim, Taeyoung Lee, Yong-Gu Sci Rep Article Non-invasive delivery of artificial implants, stents or devices in patients is vital for rapid and successful recovery. Unfortunately, because the delivery passage is often narrower than the size of the delivered object, a compromise between the shape that is effective at the targeted location and a thin form that allows smooth unobstructed travel to the destination is needed. We address this problem through two key technologies: 3D printing and shape memory polymers (SMPs). 3D printing can produce patient-customizable objects, and SMPs can change their initially formed shape to the final desired shape through external stimulation. Using these two technologies, we examine the design and fabrication of bifurcated stents. This study presents a mock-up where blood vessels are fabricated using moulded silicon, which supports the effectiveness of the proposed method. The experimental results reveal that a bifurcated stent with a kirigami structure can smoothly travel inside a vessel without being obstructed by branched parts. We believe that this work can improve the success rate of stent insertion operations in medicine. Nature Publishing Group UK 2018-09-17 /pmc/articles/PMC6141457/ /pubmed/30224641 http://dx.doi.org/10.1038/s41598-018-32129-3 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Kim, Taeyoung Lee, Yong-Gu Shape transformable bifurcated stents |
title | Shape transformable bifurcated stents |
title_full | Shape transformable bifurcated stents |
title_fullStr | Shape transformable bifurcated stents |
title_full_unstemmed | Shape transformable bifurcated stents |
title_short | Shape transformable bifurcated stents |
title_sort | shape transformable bifurcated stents |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141457/ https://www.ncbi.nlm.nih.gov/pubmed/30224641 http://dx.doi.org/10.1038/s41598-018-32129-3 |
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