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Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance

The true clinical significance of Lodderomyces elongisporus remains underestimated as a result of problems associated with its identification by the VITEK 2 yeast identification system. Here we describe a case of L. elongisporus primary progressive fungaemia in a woman with no known risk factors for...

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Autores principales: Al-Obaid, K., Ahmad, S., Joseph, L., Khan, Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141678/
https://www.ncbi.nlm.nih.gov/pubmed/30245829
http://dx.doi.org/10.1016/j.nmni.2018.07.004
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author Al-Obaid, K.
Ahmad, S.
Joseph, L.
Khan, Z.
author_facet Al-Obaid, K.
Ahmad, S.
Joseph, L.
Khan, Z.
author_sort Al-Obaid, K.
collection PubMed
description The true clinical significance of Lodderomyces elongisporus remains underestimated as a result of problems associated with its identification by the VITEK 2 yeast identification system. Here we describe a case of L. elongisporus primary progressive fungaemia in a woman with no known risk factors for invasive fungal infections. The isolate was identified by PCR sequencing of the internally transcribed spacer region of ribosomal DNA. Despite treatment with caspofungin, the patient died within 3 days of onset of fungaemia. Our literature review highlights this organism's emerging role as a bloodstream pathogen. A need for application of molecular methods for its accurate identification is emphasized.
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spelling pubmed-61416782018-09-21 Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance Al-Obaid, K. Ahmad, S. Joseph, L. Khan, Z. New Microbes New Infect New Microbes in Human The true clinical significance of Lodderomyces elongisporus remains underestimated as a result of problems associated with its identification by the VITEK 2 yeast identification system. Here we describe a case of L. elongisporus primary progressive fungaemia in a woman with no known risk factors for invasive fungal infections. The isolate was identified by PCR sequencing of the internally transcribed spacer region of ribosomal DNA. Despite treatment with caspofungin, the patient died within 3 days of onset of fungaemia. Our literature review highlights this organism's emerging role as a bloodstream pathogen. A need for application of molecular methods for its accurate identification is emphasized. Elsevier 2018-07-18 /pmc/articles/PMC6141678/ /pubmed/30245829 http://dx.doi.org/10.1016/j.nmni.2018.07.004 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle New Microbes in Human
Al-Obaid, K.
Ahmad, S.
Joseph, L.
Khan, Z.
Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance
title Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance
title_full Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance
title_fullStr Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance
title_full_unstemmed Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance
title_short Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance
title_sort lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance
topic New Microbes in Human
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141678/
https://www.ncbi.nlm.nih.gov/pubmed/30245829
http://dx.doi.org/10.1016/j.nmni.2018.07.004
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