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Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance
The true clinical significance of Lodderomyces elongisporus remains underestimated as a result of problems associated with its identification by the VITEK 2 yeast identification system. Here we describe a case of L. elongisporus primary progressive fungaemia in a woman with no known risk factors for...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141678/ https://www.ncbi.nlm.nih.gov/pubmed/30245829 http://dx.doi.org/10.1016/j.nmni.2018.07.004 |
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author | Al-Obaid, K. Ahmad, S. Joseph, L. Khan, Z. |
author_facet | Al-Obaid, K. Ahmad, S. Joseph, L. Khan, Z. |
author_sort | Al-Obaid, K. |
collection | PubMed |
description | The true clinical significance of Lodderomyces elongisporus remains underestimated as a result of problems associated with its identification by the VITEK 2 yeast identification system. Here we describe a case of L. elongisporus primary progressive fungaemia in a woman with no known risk factors for invasive fungal infections. The isolate was identified by PCR sequencing of the internally transcribed spacer region of ribosomal DNA. Despite treatment with caspofungin, the patient died within 3 days of onset of fungaemia. Our literature review highlights this organism's emerging role as a bloodstream pathogen. A need for application of molecular methods for its accurate identification is emphasized. |
format | Online Article Text |
id | pubmed-6141678 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-61416782018-09-21 Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance Al-Obaid, K. Ahmad, S. Joseph, L. Khan, Z. New Microbes New Infect New Microbes in Human The true clinical significance of Lodderomyces elongisporus remains underestimated as a result of problems associated with its identification by the VITEK 2 yeast identification system. Here we describe a case of L. elongisporus primary progressive fungaemia in a woman with no known risk factors for invasive fungal infections. The isolate was identified by PCR sequencing of the internally transcribed spacer region of ribosomal DNA. Despite treatment with caspofungin, the patient died within 3 days of onset of fungaemia. Our literature review highlights this organism's emerging role as a bloodstream pathogen. A need for application of molecular methods for its accurate identification is emphasized. Elsevier 2018-07-18 /pmc/articles/PMC6141678/ /pubmed/30245829 http://dx.doi.org/10.1016/j.nmni.2018.07.004 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | New Microbes in Human Al-Obaid, K. Ahmad, S. Joseph, L. Khan, Z. Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance |
title | Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance |
title_full | Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance |
title_fullStr | Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance |
title_full_unstemmed | Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance |
title_short | Lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance |
title_sort | lodderomyces elongisporus: a bloodstream pathogen of greater clinical significance |
topic | New Microbes in Human |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141678/ https://www.ncbi.nlm.nih.gov/pubmed/30245829 http://dx.doi.org/10.1016/j.nmni.2018.07.004 |
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