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Deficiency of MecA in Streptococcus mutans Causes Major Defects in Cell Envelope Biogenesis, Cell Division, and Biofilm Formation

MecA is an adaptor protein that guides the ClpC/P-mediated proteolysis. A S. mutans MecA-deficient mutant was constructed by double-crossover allelic exchange and analyzed for the effects of such a deficiency on cell biology and biofilm formation. Unlike the wild-type, UA159, the mecA mutant, TW416,...

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Detalles Bibliográficos
Autores principales:	De, Arpan, Jorgensen, Ashton N., Beatty, Wandy L., Lemos, Jose, Wen, Zezhang T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141683/ https://www.ncbi.nlm.nih.gov/pubmed/30254619 http://dx.doi.org/10.3389/fmicb.2018.02130

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