Cargando…

Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice

Increasing prevalence in obesity has become a significant public concern. C57BL/6J mice are prone to diet-induced obesity (DIO) when fed high-fat diet (HFD), and develop chronic inflammation and metabolic syndrome, making them a good model to analyze mechanisms whereby obesity elicits pathologies. D...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lainez, Nancy M., Jonak, Carrie R., Nair, Meera G., Ethell, Iryna M., Wilson, Emma H., Carson, Monica J., Coss, Djurdjica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141693/ https://www.ncbi.nlm.nih.gov/pubmed/30254630 http://dx.doi.org/10.3389/fimmu.2018.01992

Ejemplares similares

FRI283 Fragile X Gene Mutations Alter GnRH Neuron And Ovarian Innervation With Consequences On Reproductive Function
por: Villa, Pedro A, et al.
Publicado: (2023)

Altered GnRH neuron and ovarian innervation characterize reproductive dysfunction linked to the Fragile X messenger ribonucleoprotein (Fmr1) gene mutation
por: Villa, Pedro A., et al.
Publicado: (2023)

Overactive Reproductive Axis Due to Fragile X Gene Mutation
por: Villa, Pedro, et al.
Publicado: (2021)

Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus
por: Chen, Kuan-Hui Ethan, et al.
Publicado: (2021)

Macrophage-Regulatory T Cell Interactions Promote Type 2 Immune Homeostasis Through Resistin-Like Molecule α
por: Li, Jiang, et al.
Publicado: (2021)

SUN-468 Sex Differences in Obesity-Mediated Impairment of Reproductive Function
por: Lainez, Nancy, et al.
Publicado: (2019)

Sexual dimorphism in obesity is governed by RELMα regulation of adipose macrophages and eosinophils
por: Li, Jiang, et al.
Publicado: (2023)

Sexual dimorphism in obesity is governed by RELMα regulation of adipose macrophages and eosinophils
por: Li, Jiang, et al.
Publicado: (2023)

FRI288 Single-Cell Transcriptomics Identifies Pituitary Gland Cell Type Population Changes In Diet Induced Obesity
por: Ruggiero-Ruff, Rebecca Elizabeth, et al.
Publicado: (2023)

Orexinergic neurons in the hypothalami of an Asiatic lion, an African lion, and a Southeast African cheetah
por: Oddes, Demi, et al.
Publicado: (2022)

Reusable Multielectrode Array Technique for Electroencephalography in Awake Freely Moving Mice
por: Jonak, Carrie R., et al.
Publicado: (2018)

Cell Surface Heparan Sulfate Proteoglycan Syndecan-2 Induces the Maturation of Dendritic Spines in Rat Hippocampal Neurons
por: Ethell, Iryna M., et al.
Publicado: (1999)

In-Vitro Exposure to Endocrine Disruptors Alters Inflammatory Markers in Whole Hypothalami and Immortalized GnRH Neurons
por: Riaño, Juan Manuel, et al.
Publicado: (2021)

Automated spatio-temporal analysis of dendritic spines and related protein dynamics
por: On, Vincent, et al.
Publicado: (2017)

Decreased Anti-Müllerian hormone and Anti-Müllerian hormone receptor type 2 in hypothalami of old Japanese Black cows
por: KEREILWE, Onalenna, et al.
Publicado: (2020)

Synbindin, a Novel Syndecan-2–Binding Protein in Neuronal Dendritic Spines
por: Ethell, Iryna M., et al.
Publicado: (2000)

Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus
por: Henkemeyer, Mark, et al.
Publicado: (2003)

Epigenetic Regulation of Gonadotropin Hormone Beta Subunit Gene Expression
por: Ruggiero, Rebecca E, et al.
Publicado: (2021)

PMON12 Effects of Endocrine Disruptors on Autophagy Markers Gene Expression in Immortalized GnRH Neurons and Hypothalami of Adult Male Mice
por: Fernandez, Marina, et al.
Publicado: (2022)

Widespread Reductions of Spontaneous Neurophysiological Activity in Leber’s Disease—An Application of EEG Source Current Density Reconstruction
por: Jonak, Kamil
Publicado: (2020)

Maternal protein restriction induces alterations in insulin signaling and ATP sensitive potassium channel protein in hypothalami of intrauterine growth restriction fetal rats
por: Liu, Xiaomei, et al.
Publicado: (2013)

The Small Molecule PPARγ Agonist GL516 Induces Feeding-Stimulatory Effects in Hypothalamus Cells Hypo-E22 and Isolated Hypothalami
por: Chiavaroli, Annalisa, et al.
Publicado: (2022)

Macrophageal infiltration and microvessel density in laryngeal carcinoma: study of 52 cases
por: POPOV, T.M., et al.
Publicado: (2015)

RSV infection-elicited high MMP-12–producing macrophages exacerbate allergic airway inflammation with neutrophil infiltration
por: Makino, Airi, et al.
Publicado: (2021)

Increased 2-arachidonoyl-sn-glycerol levels normalize cortical responses to sound and improve behaviors in Fmr1 KO mice
por: Pirbhoy, Patricia S., et al.
Publicado: (2021)

N-acetylcysteine Counteracts Adipose Tissue Macrophage Infiltration and Insulin Resistance Elicited by Advanced Glycated Albumin in Healthy Rats
por: da Silva, Karolline S., et al.
Publicado: (2017)

A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders
por: Reinhard, Sarah M., et al.
Publicado: (2015)

Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast
por: Leek, R D, et al.
Publicado: (1999)

Open-label add-on treatment trial of minocycline in fragile X syndrome
por: Paribello, Carlo, et al.
Publicado: (2010)

Neural Correlates of Auditory Hypersensitivity in Fragile X Syndrome
por: Razak, Khaleel A., et al.
Publicado: (2021)

Spatial and Working Memory Is Linked to Spine Density and Mushroom Spines
por: Mahmmoud, Rasha Refaat, et al.
Publicado: (2015)

A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors
por: Mira, Emilia, et al.
Publicado: (2013)

THU125 Altered Pro-opiomelanocortin (POMC) Neuron Function Characterizes Energy Expenditure Dysfunction And Increased Body Weight Linked To Fragile X Gene Mutation
por: Ruggiero-Ruff, Rebecca Elizabeth, et al.
Publicado: (2023)

Bone Density Distribution in the Cervical Spine
por: Lovecchio, Francis, et al.
Publicado: (2022)

Sensory Processing Phenotypes in Fragile X Syndrome
por: Rais, Maham, et al.
Publicado: (2018)

Transient reduction in dendritic spine density in brain-specific profilin1 mutant mice is associated with behavioral deficits
por: Sungur, A. Özge, et al.
Publicado: (2022)

Bcl6/p53 expression, macrophages/mast cells infiltration and microvascular density in invasive breast carcinoma
por: Tamma, Roberto, et al.
Publicado: (2018)

A model of activity-dependent changes in dendritic spine density and spine structure
por: Dur-e-Ahmad, Muhammad, et al.
Publicado: (2007)

The Perineuronal ‘Safety’ Net? Perineuronal Net Abnormalities in Neurological Disorders
por: Wen, Teresa H., et al.
Publicado: (2018)

Minocycline Treatment Reverses Sound Evoked EEG Abnormalities in a Mouse Model of Fragile X Syndrome
por: Lovelace, Jonathan W., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_tc6vmu5u9ip3v70uoubko2u644