Short Lifespans of Memory T-cells in Bone Marrow, Blood, and Lymph Nodes Suggest That T-cell Memory Is Maintained by Continuous Self-Renewal of Recirculating Cells

Memory T-cells are essential to maintain long-term immunological memory. It is widely thought that the bone marrow (BM) plays an important role in the long-term maintenance of memory T-cells. There is controversy however on the longevity and recirculating kinetics of BM memory T-cells. While some ha...

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Detalles Bibliográficos
Autores principales: Baliu-Piqué, Mariona, Verheij, Myrddin W., Drylewicz, Julia, Ravesloot, Lars, de Boer, Rob J., Koets, Ad, Tesselaar, Kiki, Borghans, José A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141715/
https://www.ncbi.nlm.nih.gov/pubmed/30254637
http://dx.doi.org/10.3389/fimmu.2018.02054

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