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Grafting Neural Stem and Progenitor Cells Into the Hippocampus of Juvenile, Irradiated Mice Normalizes Behavior Deficits

The pool of neural stem and progenitor cells (NSPCs) in the dentate gyrus of the hippocampus is reduced by ionizing radiation. This explains, at least partly, the learning deficits observed in patients after radiotherapy, particularly in pediatric cases. An 8 Gy single irradiation dose was delivered...

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Detalles Bibliográficos
Autores principales:	Sato, Yoshiaki, Shinjyo, Noriko, Sato, Machiko, Nilsson, Marie K. L., Osato, Kazuhiro, Zhu, Changlian, Pekna, Marcela, Kuhn, Hans G., Blomgren, Klas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141740/ https://www.ncbi.nlm.nih.gov/pubmed/30254600 http://dx.doi.org/10.3389/fneur.2018.00715

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