Cargando…

Investigating the role of P38, JNK and ERK in LPS induced hippocampal insulin resistance and spatial memory impairment: effects of insulin treatment

Despite the consensus that neuro-inflammation and insulin resistance (IR) are two hallmarks of Alzheimer disease (AD), the molecular mechanisms responsible for the development of IR remain uncharacterized. MAPKs are signaling molecules that are implicated in the pathology of AD and have a role in IR...

Descripción completa

Detalles Bibliográficos
Autores principales: Iloun, Parisa, Abbasnejad, Zahra, Janahmadi, Mahyar, Ahmadiani, Abolhassan, Ghasemi, Rasoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141830/
https://www.ncbi.nlm.nih.gov/pubmed/30233281
http://dx.doi.org/10.17179/excli2018-1387