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The Diversity of Mammalian Hemoproteins and Microbial Heme Scavengers Is Shaped by an Arms Race for Iron Piracy

Iron is an essential micronutrient for most living species. In mammals, hemoglobin (Hb) stores more than two thirds of the body's iron content. In the bloodstream, haptoglobin (Hp) and hemopexin (Hpx) sequester free Hb or heme. Pathogenic microorganisms usually acquire iron from their hosts and...

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Detalles Bibliográficos
Autores principales: Mozzi, Alessandra, Forni, Diego, Clerici, Mario, Cagliani, Rachele, Sironi, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142043/
https://www.ncbi.nlm.nih.gov/pubmed/30271410
http://dx.doi.org/10.3389/fimmu.2018.02086