Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis

Tobacco smoke (TS) contains numerous cancer-causing agents, with polycyclic aromatic hydrocarbons (PAHs) and nitrosamines being most frequently cited as the major TS human cancer agents. Many lines of evidence seriously question this conclusion. To resolve this issue, we determined DNA adducts induc...

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Detalles Bibliográficos
Autores principales: Weng, Mao-wen, Lee, Hyun-Wook, Park, Sung-Hyun, Hu, Yu, Wang, Hsing-Tsui, Chen, Lung-Chi, Rom, William N., Huang, William C., Lepor, Herbert, Wu, Xue-Ru, Yang, Chung S., Tang, Moon-shong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142211/
https://www.ncbi.nlm.nih.gov/pubmed/29915082
http://dx.doi.org/10.1073/pnas.1804869115

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