Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3

Metastasis remains the leading cause of cancer mortality, and reactive oxygen species (ROS) signaling promotes the metastatic cascade. However, the molecular pathways that control ROS signaling relevant to metastasis are little studied. Here, we identify SIRT3, a mitochondrial deacetylase, as a regu...

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Detalles Bibliográficos
Autores principales: Lee, Jaewon J., van de Ven, Robert A. H., Zaganjor, Elma, Ng, Mei Rosa, Barakat, Amey, Demmers, Joris J. P. G., Finley, Lydia W. S., Gonzalez Herrera, Karina N., Hung, Yin Pun, Harris, Isaac S., Jeong, Seung Min, Danuser, Gaudenz, McAllister, Sandra S., Haigis, Marcia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142214/
https://www.ncbi.nlm.nih.gov/pubmed/29915029
http://dx.doi.org/10.1073/pnas.1800440115

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