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Modulation of transcriptional burst frequency by histone acetylation

Many mammalian genes are transcribed during short bursts of variable frequencies and sizes that substantially contribute to cell-to-cell variability. However, which molecular mechanisms determine bursting properties remains unclear. To probe putative mechanisms, we combined temporal analysis of tran...

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Detalles Bibliográficos
Autores principales: Nicolas, Damien, Zoller, Benjamin, Suter, David M., Naef, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142243/
https://www.ncbi.nlm.nih.gov/pubmed/29915087
http://dx.doi.org/10.1073/pnas.1722330115

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