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Modulation of transcriptional burst frequency by histone acetylation
Many mammalian genes are transcribed during short bursts of variable frequencies and sizes that substantially contribute to cell-to-cell variability. However, which molecular mechanisms determine bursting properties remains unclear. To probe putative mechanisms, we combined temporal analysis of tran...
Autores principales: | Nicolas, Damien, Zoller, Benjamin, Suter, David M., Naef, Felix |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142243/ https://www.ncbi.nlm.nih.gov/pubmed/29915087 http://dx.doi.org/10.1073/pnas.1722330115 |
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