Identification of TBX2 and TBX3 variants in patients with conotruncal heart defects by target sequencing

BACKGROUND: Conotruncal heart defects (CTDs) are heterogeneous congenital heart malformations that result from outflow tract dysplasia; however, the genetic determinants underlying CTDs remain unclear. Increasing evidence demonstrates that dysfunctional TBX2 and TBX3 result in outflow tract malforma...

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Detalles Bibliográficos
Autores principales: Xie, Huilin, Zhang, Erge, Hong, Nanchao, Fu, Qihua, Li, Fen, Chen, Sun, Yu, Yu, Sun, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142335/
https://www.ncbi.nlm.nih.gov/pubmed/30223900
http://dx.doi.org/10.1186/s40246-018-0176-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142335/
https://www.ncbi.nlm.nih.gov/pubmed/30223900
http://dx.doi.org/10.1186/s40246-018-0176-0

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