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Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells
It is generally recognized that hepatic fibrogenesis is an end result of increased extracellular matrix (ECM) production from the activation and proliferation of hepatic stellate cells (HSCs). An in-depth understanding of the mechanisms of HSC necroptosis might provide a new therapeutic strategy for...
Autores principales: | Jia, Yan, Wang, Feixia, Guo, Qin, Li, Mengmeng, Wang, Ling, Zhang, Zili, Jiang, Shuoyi, Jin, Huanhuan, Chen, Anping, Tan, Shanzhong, Zhang, Feng, Shao, Jiangjuan, Zheng, Shizhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142373/ https://www.ncbi.nlm.nih.gov/pubmed/30237126 http://dx.doi.org/10.1016/j.redox.2018.09.007 |
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